Angiotensin II, Human, FAM-Labeled

FAM-DRVYIHPF is fluorescently labeled human angiotensin II. Angiotensin II is the principal effector peptide of the renin-angiotensin system and signals primarily through angiotensin receptors to regulate vascular tone, fluid balance, cell growth and tissue remodeling. The FAM tag enables direct fluorescence detection near 494/518 nm.

• angiotensin receptor studies
• peptide uptake and localization
• renin-angiotensin system research
• fluorescence imaging

The N-terminal FAM label changes mass and physicochemical properties relative to native angiotensin II; receptor-binding or trafficking data should be interpreted using an appropriate unlabeled control.

1. Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology