Amyloid-Forming Peptide GNNQQNY

GNNQQNY is a heptapeptide from the prion-determining domain of yeast Sup35 that forms amyloid-like fibrils. Its well-characterized cross-beta spine makes it a compact model for studying amyloid nucleation, steric-zipper packing and aggregation thermodynamics.

• neuroscience and neuropeptide research
• amyloid or receptor studies
• cell-signaling assays
• structure-function studies

Exact sequence, species, terminal chemistry and stereochemistry define this reagent. Use sequence-matched controls and consistent preparation conditions.

1. Selected peer-reviewed publication