ACTH (7-38), Human

ACTH(7-38), also known as corticotropin-inhibiting peptide, is a C-terminal ACTH fragment that acts as an ACTH-receptor antagonist and lacks corticosteroidogenic activity. It is used to separate receptor antagonism from agonist ACTH signaling.

• hypothalamo-pituitary axis research
• GPCR and endocrine signaling
• stress, growth-hormone or reproductive studies
• melanocortin and ACTH fragment research

Exact peptide length, terminal amidation, pyroglutamate formation and affinity labeling are integral to product identity. Use sequence- and modification-matched controls for quantitative receptor or endocrine assays.

1. Selected peer-reviewed publication