ACTH (1-39), Human

Human ACTH(1-39) is the full-length pituitary adrenocorticotropic hormone produced from POMC processing. It activates the melanocortin-2 receptor in adrenal cortex to stimulate glucocorticoid biosynthesis and is the parent sequence for multiple ACTH fragments.

• hypothalamo-pituitary axis research
• GPCR and endocrine signaling
• stress, growth-hormone or reproductive studies
• melanocortin and ACTH fragment research

Exact peptide length, terminal amidation, pyroglutamate formation and affinity labeling are integral to product identity. Use sequence- and modification-matched controls for quantitative receptor or endocrine assays.

1. Selected peer-reviewed publication