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CD47 Peptides

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CD47 Peptides for Self-Signaling and Nanomedicine Research

CD47 peptide stealth nanoparticle mechanism

CD47-derived peptides are used in self-signaling, SIRPα binding, macrophage uptake reduction, and nanomedicine surface engineering. These formats are especially relevant for researchers studying the CD47–SIRPα axis as either an immune checkpoint pathway or a biomimetic stealth strategy for nanoparticles, liposomes, and related delivery systems.

The peptide sequence family built around GNYTCEVTELTREGETIIELK is commonly used as a CD47-derived self peptide. Depending on format, the same biological concept can be applied to binding studies, fluorescence imaging, nanoparticle decoration, or conjugation workflows.

Available CD47 Peptide Formats

Native peptides Mechanism studies, receptor binding, control peptide formats
FITC-labeled peptides Imaging, flow cytometry, uptake studies, particle tracking
DSPE-PEG conjugates Lipid nanoparticle and liposome stealth surface engineering
Conjugation-ready formats Cys- or maleimide-bearing formats for nanoparticle or protein coupling

Core Product Family

Product Main Use Link
CD47 peptide General CD47/SIRPα pathway research View Product
CD47 self peptide Minimal self-peptide motif for receptor and nanoparticle studies View Product
FITC-Ahx-CD47 peptide Fluorescence-based binding and tracking studies View Product
DSPE-PEG2000-CD47 self peptide LNP and liposome stealth engineering View Product

How to Choose the Right CD47 Peptide Format

Use the native peptide when:

  • You need a base peptide for receptor studies
  • You are comparing self-peptide motif activity
  • You want a simpler non-labeled format

Use the FITC version when:

  • You need fluorescence imaging or flow cytometry
  • You want to track peptide binding or localization
  • You are studying particle or cell-surface presentation

Use the DSPE-PEG version when:

  • You are decorating LNPs, liposomes, or micelles
  • You need a membrane-inserting stealth peptide reagent
  • You are studying macrophage uptake reduction in nanomedicine

Applications

  • Macrophage uptake reduction studies
  • Self-recognition and SIRPα binding assays
  • Lipid nanoparticle and liposome surface engineering
  • Nanomedicine biodistribution and persistence studies
  • Fluorescence-based peptide tracking

Research Use Only. Not for human or therapeutic use.