Product Name | Urotensin I |
Product Quantity | 5mg |
Catalog Number | LT2347 |
Molecular Weight | 4869.55 |
Formula | C210H340N62O67S2 |
Sequence | Asn-Asp-Asp-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Asn-Met-Ile-Glu-Met-Ala-Arg-Ile-Glu-Asn-Glu-Arg-Glu-Gln-Ala-Gly-Leu-Asn-Arg-Lys-Tyr-Leu-Asp-Glu-Val-NH2 |
Product Description | Urotensin I was found to be a close structural and biological homolog of the ovine hypothalamic corticotropin-releasing factor (CRF) and the frog skin peptide sauvagine. Urotensin I is a 41 aa peptide. which showed prolonged hypotensive effects in mammals. Urotensins are neuropeptide secreted from the urophysis in the caudal neurosecretory system of the fishes. |
Scientific Background | Urotensin I is a 41-residue synthetic peptide with the sequence Asn-Asp-Asp-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Asn-Met-Ile-Glu-Met-Ala-Arg-Ile-Glu-Asn-Glu-Arg-Glu-Gln-Ala-Gly-Leu-Asn-Arg-Lys-Tyr-Leu-Asp-Glu-Val. C-terminal amidation removes the terminal carboxylate charge. The sequence contains 1 Lys and 4 Arg residues, contributing cationic character. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
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Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
