[Tyr0] Gastric Inhibitory Peptide (23-42), human; [Tyr22] Gastri

Product Name
[Tyr0] Gastric Inhibitory Peptide (23-42), human; [Tyr22] Gastri
Product Quantity
5mg
Catalog Number
LT0733
Molecular Weight
2584.9
Formula
C119H182N34O31
Sequence
Tyr-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln
Scientific Background

[Tyr0] Gastric Inhibitory Peptide (23-42), human; [Tyr22] Gastri is a synthetic research peptide in the glucose-dependent insulinotropic polypeptide (GIP) family. GIP is a 42-residue incretin hormone produced by intestinal K cells and acting through the class B GIP receptor. N-terminal processing is functionally important; truncated forms can show reduced agonism or antagonist properties, so exact residue numbering is critical.

Research Applications
  • GIP receptor assays
  • incretin signaling studies
  • DPP-IV processing research
  • GIP fragment structure-activity studies
Experimental Notes

The exact sequence, residue range, species, terminal state, and chemical modifications should be matched to the intended assay. Fragmentation or processing can materially alter receptor selectivity, potency, aggregation, or enzymatic behavior.

Selected References
  1. Glucose-dependent insulinotropic polypeptide (GIP)
  2. GIP receptor antagonists and truncated GIP peptides
  • 5 Units in Stock
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