SIINFEKL-Cys

SIINFEKL is a well-known epitope derived from the ovalbumin protein (OVA), a major component of egg whites. It represents an 8-amino acid sequence (Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu), often referred to as OVA257-264, recognized by the immune system, particularly by CD8+ cytotoxic T lymphocytes (CTLs) in C57BL/6 mice. This peptide has become a crucial tool in immunological studies, particularly for antigen presentation, T-cell response assays, and vaccine development.

SIINFEKL-Cys is a 10-residue synthetic peptide with the sequence Arg-Glu-Pro-Arg-Glu-Ser-Glu-Asn-Thr-Ser. The sequence contains 0 Asp and 3 Glu residues, contributing anionic character near neutral pH. These sequence-derived properties describe the reagent chemically; no specific biological activity is assigned without product-specific experimental evidence.

• LC-MS/HPLC analytical method development
• sequence-specific assay controls

Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended conditions.