Recombinant Human Growth Hormone (rh-HGH)

Catalog Number:
LT1201300-GH
Packing Details:
10 IU, 1 IU = ~0.33 mg
Physical Appearance:
Freeze-dried powder
Mol. Wt.:
22.5 kDa
N-terminus Sequenced:
GFPTIPLSRL
Resources:
Escherichia coli (E. coli)
Purity:
≥95%
Endotoxin:
<1.0 EU/µg protein
Biological Activity:
The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVECs) in a range of 100~500 ng/ml.
Storage Condition:
-20°C in dark place
Storage Duration:
3 years
Description:

Human growth hormone (HGH) is a 191 amino acid non-glycosylated protein hormone secreted by the anterior pituitary gland in brain. It is one of the most important postnatal hormones. HGH plays an important role in cell proliferation, bone formation, muscle strength, organogenesis and somatic growth because its principal physiological functions are the stimulation on the rate of protein synthesis and the mobilization and utilization of fatty acids, and decline on the rate of carbohydrate utilization.

Recombinant human growth hormone is a protein that is manufactured to be nearly identical to the main form of the naturally occurring human growth hormone. This hormone can stimulate tissue growth, linear growth (height), and protein, carbohydrate, lipid, and mineral metabolism. It has approved indications in both the adult and pediatric populations. In the United States, recombinant human growth hormone is used in the pediatric population to treat short stature due to growth hormone deficiency (including idiopathic [of unknown cause] growth hormone deficiency), Turner syndrome, Noonan syndrome, Prader-Willi syndrome, short stature homeobox-containing gene (SHOX) deficiency, chronic renal insufficiency, idiopathic short stature and children small for gestational age.

This product is for research use only.

Images:
Analysis of rh-GH by SDS-PAGE
M: Protein marker standard
Lane 1: rh-HGH
Figure 1: Analysis of rh-HGH by SDS-PAGE
Proliferation of HUVECs stimulated by rh-GH for 48h
Figure 2: Proliferation of HUVECs stimulated by rh-HGH for 48h
Notes:
It is recommended that the product is reconstituted with steriled water into a final concentration of 50 µg/ml at room temperature. Store the reconstituted product in aliquots at -20 °C. Avoid multiple freeze-thaw cycles and exposure to frequent temperature changes.

The use of strong acids and alkalis, strong oxidants, and high concentrations of organic solvents should be avoided to protect the product from denaturation.
This product shall not be used for human or animal therapeutic or diagnostic use. This is for research use only.
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$40.00
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