Neurotensin, guinea pig

Neurotensin is a brain and gastrointestinal peptide is a 13 amino acid neuropeptide. Neurotensin has been suggested to be involved in neurological and mental disorders associated with altered dopaminergic transmission. High-affinity Neurotensin binding sites are present in the guinea-pig brain in regions rich in both dopamine cell bodies and terminals. Neurotensin facilitates release of substance P in the guinea-pig inferior mesenteric ganglion.