Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (LTP10113)

Product Name
Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (LTP10113)
Catalog Number
LTP10113
Quantity
100ug
Price
$563 In stock
Background
Integrin ?L?2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active ?L?2 can bind ICAM­1/CD54, ICAM­2, ICAM3 and JAM­1[2].
Description
Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from Expi293 with His tag at the C-terminal. It contains (ITGAL)&(ITGB2).
Target
Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer
Species
Mouse
Gene/Protein ID
P24063-1(ITGAL)&P11835(ITGB2)
Exact Sequence
Tyr24-His1087(ITGAL)acidic tail & Gln24-Asn702(ITGB2)basic tail
Molecular Weight
The protein has a predicted MW of 123.30 kDa(ITGAL)&79.60 kDa(ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa(ITGAL)&90-105 kDa(ITGB2) based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (LTP10113)
  • 5 Units in Stock
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