|
| Mouse ARTN Protein (LTP10441) |
|
| LTP10441 |
|
| 100ug |
|
|
$450 In stock |
| Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. |
| Recombinant Mouse ARTN Protein is expressed from Expi293 with hFc tag at the N-terminal. It contains Ala112-Gly224. |
|
| ARTN |
|
| Mouse |
|
| Q9Z0L2-1 |
|
| Ala112-Gly224 |
|
| The protein has a predicted MW of 39.4 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on the Tris-Bis PAGE result. |
|
| Immobilized Mouse GFRA3, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Mouse ARTN, hFc Tag with the EC50 of 0.12ug/ml determined by ELISA. See testing image for detail. |
|
| N-hFc |
|
| Expi293 |
|
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
|
| Less than 1EU per ug by the LAL method. |
|
| Lyophilized from 0.22 um filtered solution in 50mM Glycine,150mM NaCl (pH 3.2). Normally 8% trehalose is added as a protectant before lyophilization. |
|
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
| Shipped at ambient temperature. |
|
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 50mM Glycine,150mM NaCl (pH 3.2). |
|
|  |
