Melanotan-I is a synthetic research peptide in the melanocortin receptor agonist peptide family. Melanotan-I and melanotan-II are alpha-MSH-derived melanocortin agonist peptides. Melanotan-II is a cyclic lactam analog containing the melanocortin pharmacophore and is a potent ligand used to characterize melanocortin receptor activity. Melanotan-I is a stabilized alpha-MSH analog; exact cyclicity and substitutions determine receptor potency and selectivity.
The exact sequence, residue range, species, stereochemistry, terminal state, labels, and other modifications can materially affect activity. Match the supplied construct to the intended assay and published reference context.
