Product Name | MBP8298 DENPVVHFFKNIVTPRT |
Product Quantity | 5 mg |
Catalog Number | LT2668 |
Molecular Weight | 2013.37 |
Formula | C92H141N25O26 |
Sequence | DENPVVHFFKNIVTPRT, Asp - Glu - Asn - Pro - Val - Val - His - Phe - Phe - Lys - Asn - Ile - Val - Thr - Pro - Arg - Thr |
Purity | >95% |
CAS Number | N/A |
Product Description | MBP8298 is a synthetic peptide with a sequence corresponding to amino acid residues 82–98 of human myelin basic protein (DENPVVHFFKNIVTPRT). Dirucotide is a synthetically peptide of 17 amino acids. The peptide is a section of myelin basic protein (MBP) in humans. Dirucotide was used for the treatment of multiple sclerosis (MS). MBP8298 was evaluated in a placebo-controlled double-blinded Phase II clinical trial in patients with progressive MS. |
Scientific Background | MBP8298 DENPVVHFFKNIVTPRT is a 17-residue synthetic peptide with the sequence Asp-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
