Human uPAR/PLAUR Protein (LTP10067)

Product Name
Human uPAR/PLAUR Protein (LTP10067)
Catalog Number
LTP10067
Quantity
100ug
Price
$203 In stock
Background
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
Description
Recombinant Human uPAR/PLAUR Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Leu23-Gly305.
Target
uPAR/PLAUR
Species
Human
Gene/Protein ID
Q03405-1
Exact Sequence
Leu23-Gly305
Molecular Weight
The protein has a predicted MW of 34.36 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human uPAR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Human PLAU, His Tag with the EC50 of 9.6ng/ml determined by ELISA. See testing image for detail.
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human uPAR/PLAUR Protein (LTP10067)
  • 5 Units in Stock
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