Human Her4/ErbB4 Protein (LTP10612)

Product Name
Human Her4/ErbB4 Protein (LTP10612)
Catalog Number
LTP10612
Quantity
100ug
Price
$324 In stock
Background
ErbB4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between ErbB4 and type 2 diabetes and obesity. ErbB4 may play an important role in glucose homeostasis and lipogenesis. ErbB4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS.
Description
Recombinant Human Her4/ErbB4 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Gln26-Pro651.
Target
Her4/ErbB4
Species
Human
Gene/Protein ID
Q15303-1
Exact Sequence
Gln26-Pro651
Molecular Weight
The protein has a predicted MW of 96.6 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human Her4/ErbB4 Protein (LTP10612)
  • 5 Units in Stock
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