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| Human CDH17/Cadherin 17 Protein (LTP10478) |
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| LTP10478 |
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| 100ug |
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$450 In stock |
| Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Recombinant Human CDH17/Cadherin 17 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln23-Met787. |
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| CDH17/Cadherin 17 |
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| Human |
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| Q12864-1 |
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| Gln23-Met787 |
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| The protein has a predicted MW of 86.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human CDH17, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA. See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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