Human CDH17/Cadherin 17 Domain 5-7 Protein (LTP10044)

Product Name
Human CDH17/Cadherin 17 Domain 5-7 Protein (LTP10044)
Catalog Number
LTP10044
Quantity
100ug
Price
$586 In stock
Background
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Description
Recombinant Human CDH17/Cadherin 17 Domain 5-7 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Glu450-Gly777.
Target
CDH17/Cadherin 17 Domain 5-7
Species
Human
Gene/Protein ID
Q12864
Exact Sequence
Glu450-Gly777
Molecular Weight
The protein has a predicted MW of 36.79 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human CDH17/Cadherin 17 Domain 5-7 Protein (LTP10044)
  • 5 Units in Stock
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