Histone H4 (8-30) K20Me2-WGK(Biotin)

H4K20me2 is an abundant histone modification involved in DNA-damage signaling and recognition by methyl-lysine reader proteins. The biotinylated H4(8-30) construct supports pull-down and reader-binding assays.

• DNA damage response research
• H4K20Me2 reader binding
• streptavidin pull-downs
• methylation-state comparisons

The exact K20 dimethyl state must remain separate from K20Me1 and K20Me3. Current family/product records confirm the sequence and MW 3171.

1. Degrees make all the difference: the multifunctionality of histone H4 lysine 20 methylation