Catalog Number | LT9048 |
Product Name | Histone H4 (1-21) K8Ac-GGK(Biotin) |
Product Quantity | 1 mg |
Sequence | Ac-SGRGKGG-K(Ac)-GLGKGGAKRHRKV-GGK(Biotin) |
Molecular Weight | 2644.2 |
Purity | ≥95% |
| Scientific Background | H4K8ac is a site-specific histone H4 acetylation mark implicated in transcriptional activation and recruitment of bromodomain-containing chromatin-remodeling proteins. This N-terminally acetylated, biotinylated H4 peptide provides a defined ligand for modification-sensitive binding assays. |
| Research Applications | - H4K8ac binding studies
- bromodomain research
- chromatin remodeling studies
- histone acetylation assays
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| Experimental Notes | LifeTein one-letter sequence is used because the current three-letter text on the product page is internally inconsistent. The one-letter sequence, molecular weight and modification description agree on H4K8 acetylation. |
| Selected References | - Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro
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