Histone H3 (44-63)

Histone H3(44-63) covers a central region of H3 outside the heavily modified N-terminal tail. Defined internal histone fragments are useful for antibody specificity studies, protein-interaction mapping and comparative biochemical assays.

• histone antibody specificity
• protein interaction mapping
• chromatin biochemistry
• epitope mapping

This internal H3 fragment should not be described as an N-terminal histone-tail peptide. Its applications are primarily as a sequence-defined internal H3 control or binding reagent.

1. Histone H3 lysine 36 methylation is associated with transcriptional elongation and recruits chromatin-regulatory proteins