Product Name | Galanin, human |
Product Quantity | 5mg |
Catalog Number | LT1461 |
Molecular Weight | 3157.44 |
Formula | C139H210N42O43 |
Sequence | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser |
Product Description | Galanin, a 29 or 30 (in human) amino acid neuropeptide, is found in the central and peripheral nervous systems and displays several important physiological activities. These actions are mediated through distinct G protein-coupled receptors. It is involved in regulation of food intake, metabolism and reproduction, regulation of neurotransmitter and hormone release, nociception, intestinal contraction and secretion, and more recently in nervous system development and response to injury. |
Scientific Background | Galanin, human is a synthetic research peptide in the galanin-family neuropeptide family. Galanin is a neuropeptide whose N-terminal region is particularly important for high-affinity receptor recognition. Galanin(1-29), galanin(1-16), galanin-like peptide, and related fragments or analogs are used to study GalR1, GalR2, and GalR3 signaling and the structural requirements for receptor binding. |
Research Applications | - galanin receptor binding assays
- GalR1/GalR2/GalR3 signaling studies
- N-terminal fragment structure-activity comparisons
- neuropeptide processing and stability studies
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Experimental Notes | The exact sequence, species, residue range, terminal state, labels, stereochemistry, and post-translational modifications should be considered when comparing this reagent with the native peptide. Receptor potency and assay behavior should be validated in the intended experimental system. |
Selected References | - N-terminal galanin fragments and receptor binding
- Structural requirements for galanin receptor interaction
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