Cys-beta-Amyloid (1-40)

An N-terminal cysteine has been added to human Aβ(1-40), creating a thiol-containing derivative useful for site-directed conjugation, immobilization and probe construction. The underlying Aβ1-40 sequence retains the major cerebrovascular amyloid peptide context.

• thiol-selective conjugation
• Aβ immobilization studies
• aggregation research
• fluorescent or surface-probe construction

The added cysteine is part of the exact sequence and can alter oxidation or aggregation behavior. LifeTein documentation verifies MW 4433 and ≥95% purity for this 1 mg form; price is left TBD.

1. Specific binding of amyloid-beta-protein to IMR-32 neuroblastoma cell membrane