| Cynomolgus OSMR Protein (LTP10097) |
| LTP10097 |
| 100ug |
|
$473 In stock |
| OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. |
| Recombinant Cynomolgus OSMR Protein is expressed from Expi293 with His tag at the C-terminal. It contains Glu28-Ser737. |
| OSMR |
| Cynomolgus |
| A0A2K5UFW5 |
| Glu28-Ser737 |
| The protein has a predicted MW of 82.04 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on the Tris-Bis PAGE result. |
| Immobilized Cynomolgus OSMR, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA. See testing image for detail. |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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