Cynomolgus NKp46/NCR1/CD335 Protein (LTP10418)

Product Name
Cynomolgus NKp46/NCR1/CD335 Protein (LTP10418)
Catalog Number
LTP10418
Quantity
100ug
Price
$450 In stock
Background
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
Description
Recombinant Cynomolgus NKp46/NCR1/CD335 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Pro22-Asn254.
Target
NKp46/NCR1/CD335
Species
Cynomolgus
Gene/Protein ID
Q95JB9
Exact Sequence
Pro22-Asn254
Molecular Weight
The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Cynomolgus NKp46, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in 20mM Tris, 150mM NaCl, 100mM L-Arginine (pH 8.2). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Cynomolgus NKp46/NCR1/CD335 Protein (LTP10418)
  • 5 Units in Stock

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$450.00

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