Product Name | C-Type Natriuretic Peptide (1-22), human |
Product Quantity | 5mg |
Catalog Number | LT1301 |
Molecular Weight | 2197.64 |
Formula | C93H157N27O28S3 |
Sequence | Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(Disulfide bridge:Cys6-Cys22) |
Product Description | Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. C-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and most major endocrine glands. C-type natriuretic peptide has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function. |
Scientific Background | C-Type Natriuretic Peptide (1-22), human is a 24-residue synthetic peptide with the sequence Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Cys-Cys. The sequence contains 4 cysteine residues, providing potential thiol/disulfide chemistry when the thiol is available; contains 2 Lys and 1 Arg residues, contributing cationic character. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - thiol-selective conjugation or immobilization studies
- LC-MS/HPLC analytical method development
- sequence-specific assay controls
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Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
