Scientific Background | Biotin-PACAP (1-38), amide, human, ovine, rat is a synthetic research peptide in the PACAP family. The listed sequence/design is Biotin-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2. PACAP is a class B GPCR peptide ligand that activates PAC1 as well as VPAC receptors. Fragments and analogs are useful for dissecting receptor recognition and signaling. |
Experimental Notes | Because this product may be a fragment, substituted analog, stereochemical variant, or terminally modified form, its activity should not be assumed to be identical to the native parent peptide. Peptide solubility, aggregation, adsorption to surfaces, and stability can vary with sequence, concentration, pH, ionic strength, and terminal modifications, so assay-specific reconstitution and storage conditions should be validated experimentally. |
