SIRT2 peptide, Ac-Gln-Pro-Lys-Lys(AC)-AMC

Product Name
SIRT2 peptide, Ac-Gln-Pro-Lys-Lys(AC)-AMC
Product Quantity
100.3 mg
Catalog Number
LT12023
Molecular Weight
741.86
Formula
C36H53N8O9
Sequence
Ac-Gln-Pro-Lys-Lys(AC)-AMC
Purity
99.03%
Product Description
The fluorophore can be analyzed with an excitation wavelength of 350-360 nm and an emission wavelength of 450-465 nm.
Scientific Background

SIRT2 peptide, Ac-Gln-Pro-Lys-Lys(AC)-AMC is a synthetic research peptide in the SIRT2 deacetylase peptide substrate family. SIRT2 is an NAD+-dependent lysine deacetylase. Acetyl-lysine-containing fluorogenic peptides are used as defined SIRT2 substrates for enzyme-activity measurements and inhibitor screening, where deacetylation is coupled to reporter development.

Research Applications
  • SIRT2 activity assays
  • NAD+-dependent deacetylase studies
  • SIRT2 inhibitor screening
  • fluorogenic substrate assays
Experimental Notes

The exact sequence, residue range, species, stereochemistry, terminal state, labels, and other modifications can materially affect activity. Match the supplied construct to the intended assay and published reference context.

Selected References
  1. SIRT2 fluorogenic acetyl-lysine peptide substrate literature
  • 1 Units in Stock
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