Product Name | PolyLys-Cys-SH |
Product Quantity | 5mg |
Catalog Number | LT12001 |
Molecular Weight | 890.20 |
Formula | C39H79N13O8S1 |
Sequence | KKKKKKC, Poly-lysine facilitates the attachment of cells and proteins to solid surfaces in biological applications. Using high pH poly-lysine coating, such as pH 8.5, in borate buffer to enhance the adsorption. Poly-Lysine enhances electrostatic interaction between negatively-charged ions of the cell membrane and positively-charged surface ions of attachment factors on the culture surface. When adsorbed to the culture surface, it increases the number of positively-charged sites available for cell binding. High concentration poly-lysine of 7.5ug/cm² is recommended for the surface area of your culture dish or coverslips.
Related products: Polylysine, Poly-L-Lysine, K20; Polylysine, Poly-L-Lysine, KKKKKKKKKK, K10 |
Purity | >95% |
Scientific Background | PolyLys-Cys-SH is a 227-residue synthetic peptide with the sequence Lys-Lys-Lys-Lys-Lys-Lys-Cys-Leu-Tyr-Ser-Ile-Asn-Glu-Phe-Ala-Cys-Ile-Leu-Ile-Thr-Ala-Thr-Glu-Ser-Thr-His-Glu-Ala-Thr-Thr-Ala-Cys-His-Met-Glu-Asn-Thr-Cys-Glu-Leu-Leu-Ser-Ala-Asn-Asp-Ile-Asn-His-Ile-Gly-His-Pro-His-Leu-Tyr-Ser-Ile-Asn-Glu-Ala-Ser-Pro-His-Ile-Asn-Glu-Asn-His-Ala-Asn-Cys-Glu-Thr-His-Glu-Leu-Tyr-Ser-Ile-Asn-Glu-Glu-Asn-His-Ala-Asn-Cys-Glu-Ser-Asn-Glu-Gly-Ala-Thr-Ile-Val-Glu-Leu-Tyr-Cys-His-Ala-Arg-Gly-Glu-Asp-Thr-His-Glu-Cys-Glu-Leu-Leu-Ala-Asn-Asp-Cys-His-Ala-Arg-Gly-Glu-Asp-Ala-Thr-Thr-Ala-Cys-His-Met-Glu-Asn-Thr-Thr-His-Glu-Trp-His-Glu-Asn-Thr-His-Glu-Ile-Thr-Ile-Asn-Cys-Arg-Glu-Ala-Ser-Glu-Ser-Thr-His-Glu-Cys-His-Ala-Arg-Gly-Glu-Asp-Ser-Ile-Thr-Glu-Ser-Cys-Glu-Leu-Leu-His-Ile-Gly-His-Leu-Tyr-Ser-Ile-Asn-Glu-Cys-Met-Ile-Ser-Thr-His-Glu-Ala-Arg-Glu-Ala-Asp-Ile-Ser-His-Arg-Glu-Leu-Ala-Thr-Glu-Asp-Leu-Tyr-Ser-Ile-Asn-Glu-Leu-Tyr-Ser-Ile-Asn-Glu-Lys-Lys-Lys-Lys-Lys-Lys-Lys-Lys-Lys-Lys. The sequence contains 14 cysteine residues, which can support thiol-selective conjugation or disulfide chemistry when the thiol group is available; is enriched in basic residues (16 Lys and 6 Arg), giving the sequence a cationic character under many aqueous conditions; contains 9 aromatic residues (Phe/Trp/Tyr), which can contribute to hydrophobic or aromatic interactions. No specific receptor, enzyme, pathway, disease association, or biological activity is assigned to this peptide without product-specific experimental evidence. |
Research Applications | - thiol-selective conjugation or immobilization studies
- LC-MS/HPLC analytical method development
- sequence-specific assay controls
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Experimental Notes | Sequence-derived chemical properties are provided to support reagent selection and experimental planning. They do not establish a biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
