Product Name | Pal-GHK |
Product Quantity | 5mg, gram or kilogram scale peptides available upon request |
Catalog Number | 6303 |
Category | Tripeptide-1, GHK, CAS Number:147732-56-7 |
Sequence | Pal-GHK, Pal-Gly-His-Lys; C16-GHK; C16-GK-3 ; Palmitoyl Oligopeptide; Palmitoyl Tripeptide-1 |
Purity | 98 % |
Modifications | Pal-GHK is a form of the extracellular matrix-derived peptide GHK containing palmitic acid, which allows it to penetrate the stratum corneum to the epidermal and dermal skin layers. Pal-GHK increases collagen synthesis in human skin fibroblasts in vitro. It reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light. It has been used with the zwitterionic surfactant C12 dodecyldimethylamine oxide (C12DMAO) to study self-assembly of the mixture into aggregates, ribbons, and nanobelts. Pal-GHK has also been used as an internal standard for the quantification of pal-KTTKS in anti-wrinkle creams by LC-MS/MS. |
Scientific Background | Pal-GHK is a 3-residue synthetic peptide with the sequence Gly-His-Lys. palmitoylation introduces a hydrophobic lipid group. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
