Neuropeptide AF (hNPAF),Human

Neuropeptide AF (hNPAF), Human is a synthetic research peptide in the neuropeptide AF (NPAF) family. Neuropeptide AF is an RFamide-related peptide within the NPFF signaling system. NPAF can interact with NPFF receptor subtypes and has been used to investigate receptor pharmacology and peripheral metabolic signaling. Relative affinity and efficacy can differ from NPFF, so NPAF is useful as a comparative RFamide ligand.

• NPFF receptor assays
• RFamide ligand comparisons
• adipocyte signaling studies
• peptide-receptor pharmacology

The exact sequence, isoform, residue substitutions, amidation, stereochemistry, labels, and other chemical modifications can change activity substantially. For receptor-activating peptides and membrane-active peptides, concentration and assay format are especially important and should be matched to the intended experimental system.

1. Neuropeptide AF and FF modulation of adipocyte metabolism
2. Functional differences between NPFF1 and NPFF2 receptor coupling