| Mouse NKG2A&CD94 Protein (LTP10626) |
| LTP10626 |
| 100ug |
|
$473 In stock |
| The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies. |
| Recombinant Mouse NKG2A&CD94 Protein is expressed from Expi293 with mFc (IgG1) tag at the C-terminal. It contains Asn98-Ile244(NKG2A)&Ile32-Ile179(CD94). |
| NKG2A&CD94 |
| Mouse |
| Q9WU31(NKG2A)&O54707(CD94) |
| Asn98-Ile244(NKG2A) & Ile32-Ile179(CD94) |
| The protein has a predicted MW of18.3 kDa (CD94)&43.1 kDa (NKG2A). Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
| 0 |
| C-mFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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