Mouse IL-18 R1/CD218a Protein (LTP10408)

Product Name
Mouse IL-18 R1/CD218a Protein (LTP10408)
Catalog Number
LTP10408
Quantity
100ug
Price
$180 In stock
Background
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-? production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-? production in response to IL-18 stimulation.
Description
Recombinant Mouse IL-18 R1/CD218a Protein is expressed from Expi293 with His tag at the C-terminal. It contains Lys20-Gly326.
Target
IL-18 R1/CD218a
Species
Mouse
Gene/Protein ID
Q61098
Exact Sequence
Lys20-Gly326
Molecular Weight
The protein has a predicted MW of 36.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Mouse IL-18 R1/CD218a Protein (LTP10408)
  • 5 Units in Stock
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