Mouse GITR/TNFRSF18 Protein (LTP10805)

Product Name
Mouse GITR/TNFRSF18 Protein (LTP10805)
Catalog Number
LTP10805
Quantity
100ug
Price
$406 In stock
Background
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Description
Recombinant Mouse GITR/TNFRSF18 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ser22-His153.
Target
GITR/TNFRSF18
Species
Mouse
Gene/Protein ID
Q8C4K3
Exact Sequence
Ser22-His153
Molecular Weight
The protein has a predicted MW of 15.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Mouse GITR/TNFRSF18 Protein (LTP10805)
  • 5 Units in Stock
Ask a Question

$406.00

Add to Cart: