Mouse DR3/TNFRSF25 Protein (LTP10083)

Product Name
Mouse DR3/TNFRSF25 Protein (LTP10083)
Catalog Number
LTP10083
Quantity
100ug
Price
$473 In stock
Background
TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3.
Description
Recombinant Mouse DR3/TNFRSF25 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln31-Met196.
Target
DR3/TNFRSF25
Species
Mouse
Gene/Protein ID
B1AWN9
Exact Sequence
Gln31-Met196
Molecular Weight
The protein has a predicted MW of 18.79 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 4.56 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Mouse DR3/TNFRSF25 Protein (LTP10083)
  • 5 Units in Stock
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