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| Mouse DDR1 Protein (LTP10280) |
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| LTP10280 |
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| 100ug |
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$406 In stock |
| Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1's biology is elusive, with unknown downstream activation pathways; however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts. |
| Recombinant Mouse DDR1 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Asp22-Ala415. |
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| DDR1 |
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| Mouse |
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| Q03146-1 |
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| Asp22-Ala415 |
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| The protein has a predicted MW of 44.9 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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