Mouse CRTAM Protein (LTP10403)

Product Name
Mouse CRTAM Protein (LTP10403)
Catalog Number
LTP10403
Quantity
100ug
Price
$360 In stock
Background
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFN? by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.
Description
Recombinant Mouse CRTAM Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ala17-Gly289.
Target
CRTAM
Species
Mouse
Gene/Protein ID
Q149L7-1
Exact Sequence
Ala17-Gly289
Molecular Weight
The protein has a predicted MW of 31.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Mouse CRTAM Protein (LTP10403)
  • 5 Units in Stock
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