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| Mouse AGER Protein (LTP10173) |
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| LTP10173 |
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| 100ug |
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$383 In stock |
| The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NF?B, Akt, p38, and MAP kinases) that initiate and perpetuate an unfavorable proinflammatory state. |
| Recombinant Mouse AGER Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gly23-Ala340. |
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| RAGE |
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| Mouse |
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| NP_031451.2 |
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| Gly23-Ala340 |
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| The protein has a predicted MW of 34.85 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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