Human/Cynomolgus/Rhesus macaque ROR1 Protein (LTP10890)

Product Name
Human/Cynomolgus/Rhesus macaque ROR1 Protein (LTP10890)
Catalog Number
LTP10890
Quantity
100ug
Price
$203 In stock
Background
ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),  is a member of  the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.
Description
Recombinant Human/Cynomolgus/Rhesus macaque ROR1 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Gln30-Glu403.
Target
ROR1
Species
Human/Cynomolgus/Rhesus macaque
Gene/Protein ID
Q01973-1
Exact Sequence
Gln30-Glu403
Molecular Weight
The protein has a predicted MW of 68.8 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human/Cynomolgus/Rhesus macaque ROR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR1 Antibody, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA. See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human/Cynomolgus/Rhesus macaque ROR1 Protein (LTP10890)
  • 5 Units in Stock

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