Human VEGF R3/FLT4 Protein (LTP10241)

Product Name
Human VEGF R3/FLT4 Protein (LTP10241)
Catalog Number
LTP10241
Quantity
100ug
Price
$473 In stock
Background
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
Description
Recombinant Human VEGF R3/FLT4 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Tyr25-Ile776.
Target
VEGF R3/FLT4
Species
Human
Gene/Protein ID
P35916-1
Exact Sequence
Tyr25-Ile776
Molecular Weight
The protein has a predicted MW of 111.3 kDa. Due to glycosylation, the protein migrates to 135-155 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human VEGF-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF R3, hFc Tag with the EC50 of 19.8ng/ml determined by ELISA. See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in 50mM Tris, 150mM NaCl, 100mM Glycine (pH 7.5). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human VEGF R3/FLT4 Protein (LTP10241)
  • 5 Units in Stock
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