| Human TROP-2/TACSTD2 Protein (LTP11079) |
| LTP11079 |
| 100ug |
|
$270 In stock |
| Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. |
| Recombinant Human TROP-2/TACSTD2 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains His27-Thr274. |
| TROP-2/TACSTD2 |
| Human |
| P09758 |
| His27-Thr274 |
| The protein has a predicted MW of 54.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human TROP-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA. See testing image for detail. |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
|  |