Human TROP-2/TACSTD2 Protein (LTP11079)

Product Name
Human TROP-2/TACSTD2 Protein (LTP11079)
Catalog Number
LTP11079
Quantity
100ug
Price
$270 In stock
Background
Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Description
Recombinant Human TROP-2/TACSTD2 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains His27-Thr274.
Target
TROP-2/TACSTD2
Species
Human
Gene/Protein ID
P09758
Exact Sequence
His27-Thr274
Molecular Weight
The protein has a predicted MW of 54.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human TROP-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA. See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human TROP-2/TACSTD2 Protein (LTP11079)
  • 5 Units in Stock

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