Human Survivin 2B (HLA-A*24:02) Tetramer Protein (LTP10106)

Product Name
Human Survivin 2B (HLA-A*24:02) Tetramer Protein (LTP10106)
Catalog Number
LTP10106
Quantity
100ug
Price
$1350 In stock
Background
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
Description
Recombinant Human Survivin 2B(HLA-A*24:02) Tetramer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal,tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and AYACNTSTL peptide.
Target
Survivin 2B (HLA-A*24:02) Tetramer
Species
Human
Gene/Protein ID
AAA59600.1(HLA-A*24:02)&P61769(B2M)&AYACNTSTL
Exact Sequence
Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and AYACNTSTL peptide
Molecular Weight
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human Survivin 2B (HLA-A*24:02) Tetramer Protein (LTP10106)
  • 5 Units in Stock

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