Human SLAMF7/CRACC/CD319 Protein (LTP10818)

Product Name
Human SLAMF7/CRACC/CD319 Protein (LTP10818)
Catalog Number
LTP10818
Quantity
100ug
Price
$305 In stock
Background
CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.
Description
Recombinant Human SLAMF7/CRACC/CD319 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Ser23-Met226.
Target
SLAMF7/CRACC/CD319
Species
Human
Gene/Protein ID
Q9NQ25-1
Exact Sequence
Ser23-Met226
Molecular Weight
The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human SLAMF7, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-SLAMF7 Antibody, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA. See testing image for detail.
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human SLAMF7/CRACC/CD319 Protein (LTP10818)
  • 5 Units in Stock
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