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| Human OX40/TNFRSF4/CD134 Protein (LTP10764) |
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| LTP10764 |
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| 100ug |
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$339 In stock |
| Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
| Recombinant Human OX40 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Leu29-Ala216. |
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| OX40/TNFRSF4/CD134 |
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| Human |
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| P43489 |
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| Leu29-Ala216 |
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| The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 70-78 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human OX40 Ligand (Trimer) , His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human OX40, hFc Tag with the EC50 of 0.27ug/ml determined by ELISA. See testing image for detail. |
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| C-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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