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| Human MERTK/Mer Protein (LTP10117) |
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| LTP10117 |
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| 100ug |
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$406 In stock |
| MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. |
| Recombinant Human MERTK/Mer Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ala21-Ile505. |
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| MERTK/Mer |
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| Human |
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| Q12866-1 |
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| Ala21-Ile505 |
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| The protein has a predicted MW of 53.73 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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