Human MAGE-A3 (HLA-A*01:01) Tetramer Protein (LTP10137)

Product Name
Human MAGE-A3 (HLA-A*01:01) Tetramer Protein (LTP10137)
Catalog Number
LTP10137
Quantity
100ug
Price
$1350 In stock
Background
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
Description
Recombinant Human MAGE-A3(HLA-A*01:01) Tetramer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal, tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M) and EVDPIGHLY peptide.
Target
MAGE-A3 (HLA-A*01:01) Tetramer
Species
Human
Gene/Protein ID
Q5SUL5(HLA-A*01:01)&P61769(B2M)&EVDPIGHLY
Exact Sequence
Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M)and EVDPIGHLY peptide
Molecular Weight
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human MAGE-A3 (HLA-A*01:01) Tetramer Protein (LTP10137)
  • 5 Units in Stock
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