Human LILRB5/CD85c/LIR-8 Protein (LTP10898)

Product Name
Human LILRB5/CD85c/LIR-8 Protein (LTP10898)
Catalog Number
LTP10898
Quantity
100ug
Price
$473 In stock
Background
LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.
Description
Recombinant Human LILRB5/CD85c/LIR-8 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Arg18-His456.
Target
LILRB5/CD85c/LIR-8
Species
Human
Gene/Protein ID
O75023-1
Exact Sequence
Arg18-His456
Molecular Weight
The protein has a predicted MW of 49.9 kDa. Due to glycosylation, the protein migrates to 67-72 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human LILRB5/CD85c/LIR-8 Protein (LTP10898)
  • 5 Units in Stock

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