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| Human LILRB3/CD85a/ILT5 Protein (LTP10900) |
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| LTP10900 |
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| 100ug |
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$406 In stock |
| Leukocyte immunoglobulin-like receptor subfamily B (LILRB3), also known as ILT5, LIR3, and CD85a, is an immunoglobulin superfamily member that is involved in immune regulation. Subfamily B members have cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that inhibit signaling events via phosphatase SHP-1.LILRB3 may act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. |
| Recombinant Human LILRB3/CD85a/ILT5 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gly24-Glu443. |
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| LILRB3/CD85a/ILT5 |
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| Human |
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| O75022-1 |
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| Gly24-Glu443 |
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| The protein has a predicted MW of 50 kDa. Due to glycosylation, the protein migrates to 60-72 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human LILRB3, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LILRB3 Antibody, hFc Tag with the EC50 of 27.3ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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