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| Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (LTP10162) |
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| LTP10162 |
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| 100ug |
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$563 In stock |
| The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response. |
| Recombinant Human Integrin alpha X beta 2(ITGAX&ITGB2) Heterodimer Protein is expressed from Expi293 with His tag at the C-terminal. It contains Phe20-Pro1107(ITGAX)&Gln23-Asn700(ITGB2). |
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| Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer |
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| Human |
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| P20702-1(ITGAX)&P05107-1(ITGB2) |
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| Phe20-Pro1107(ITGAX) & Gln23-Asn700(ITGB2) |
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| The protein has a predicted MW of 125.50 kDa(ITGAX)&79.50 kDa(ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa(ITGAX)&85-95 kDa(ITGB2) kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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