Human IL-4 R alpha/CD124 Protein (LTP10773)

Product Name
Human IL-4 R alpha/CD124 Protein (LTP10773)
Catalog Number
LTP10773
Quantity
100ug
Price
$406 In stock
Background
Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
Description
Recombinant Human IL-4 R alpha/CD124 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gly24-His232.
Target
IL-4 R alpha/CD124
Species
Human
Gene/Protein ID
P24394-1
Exact Sequence
Gly24-His232
Molecular Weight
The protein has a predicted MW of 24.7 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human IL-4 R alpha, His Tag at 1ug/ml (100ul/Well). Dose response curve for Biotinylated Human IL-4, His Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IL-4 R alpha/CD124 Protein (LTP10773)
  • 5 Units in Stock
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